Diet high in sugar linked to Alzheimer’s disease

  • A diet high in sugar could lead to Alzheimer’s disease, according to a study that has found a link between sugar consumption and the brain impairment.
  • According to researchers from the University of Bath and King’s College London, the study offers the first evidence to explain why abnormally high blood sugar levels, or hyperglycaemia, have an impact on cognitive function.
  • When levels of sugar pass the threshold, they restrict the performance of a vital protein, which normally fights the brain inflammation associated with dementia, researchers said. Brain samples of 30 patients were used in the study.

What is Alzheimer’s disease:

  • Alzheimer’s disease (AD), also known as just Alzheimer’s, is a chronic neurodegenerative disease that usually starts slowly and gets worse over time.
  • It is the cause of 60% to 70% of cases of dementia.
  • The most common early symptom is difficulty in remembering recent events (short-term memory loss).
  • As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, not managing self care, and behavioural issues.
  • As a person’s condition declines, they often withdraw from family and society.
  • Gradually, bodily functions are lost, ultimately leading to death. 
  • Although the speed of progression can vary, the average life expectancy following diagnosis is three to nine years.

Signs and Symptoms

  • Memory problems are typically one of the first signs of cognitive impairment related to Alzheimer’s disease. Some people with memory problems have a condition called mild cognitive impairment (MCI). In MCI, people have more memory problems than normal for their age, but their symptoms do not interfere with their everyday lives. Movement difficulties and problems with the sense of smell have also been linked to MCI. Older people with MCI are at greater risk for developing Alzheimer’s, but not all of them do. Some may even go back to normal cognition.
  • The first symptoms of Alzheimer’s vary from person to person. For many, decline in non-memory aspects of cognition, such as word-finding, vision/spatial issues, and impaired reasoning or judgment, may signal the very early stages of Alzheimer’s disease. Researchers are studying biomarkers (biological signs of disease found in brain images, cerebrospinal fluid, and blood) to see if they can detect early changes in the brains of people with MCI and in cognitively normal people who may be at greater risk for Alzheimer’s. Studies indicate that such early detection may be possible, but more research is needed before these techniques can be relied upon to diagnose Alzheimer’s disease in everyday medical practice.

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