RNAi

Context:

RNAi is a gene silencing technology that inhibits protein synthesis in target cells using double-stranded RNA. Same result is achieved by Antisense technology through single-stranded RNA.

Other Facts:

  • RNAi technologies are now known to formulate drugs capable of reducing cholesterol levels by half. The technology also finds immense importance in treating acute viral infections like acquired immunodeficiency syndrome (AIDS),  because of the well-studied life cycle and pattern of gene expression of the human immunodeficiency virus (HIV).
  • Promising results have been shown by Antisense technology in producing a variety of tomato with increased shelf-life commonly known as Flavr Savr.
  • It can be said that, in the near future, antisense technology could be used in targeting cancer.

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